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2- cyano -5- fluorine benzyl bromide

2- cyano -5- fluorine benzyl bromide

Short Description:

CAS no:421552-12-7

Chemical properties: Trelagliptin succinate Intermediates


Product Detail

Product Tags

Uses

2- cyano -5- fluorine benzyl bromide is used as the intermediate of Trelagliptin succinate .
Trogliptin succinate is a dipeptidyl peptidase Ⅳ (DPP - Ⅳ) inhibitor developed by Takeda (Takeda Pharmaceutical Co., Ltd.) in Japan. It can selectively and continuously inhibit DPP - Ⅳ and control blood glucose level. Clinical trials show that the drug has good safety and effectiveness. Once a week can effectively control the blood glucose level and improve the medication compliance of patients. In May, 2015, the drug was approved by Japan PMDA to be listed for the treatment of diabetes.

Resource-integrated Product Line

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Certificate

JIN DUN Medical has ISO qualification and meets GMP production standards, employed domestic and foreign drug synthesis experts with rich experience to guide company's R&D.

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Advantages on Medical Customization

TECHNOL OGY ADVANTAGES
●High Pressure Catalytic Hydrogenation . High Pressure Hydrogenolysis Reaction . Cryogenic Reaction (<-78%C)
●Aromatic Heterocyclic Synthesis
●Rearrangement Reaction
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira . Gignard Reaction

JIN DUN R&D

Equipments

Our Lab has various experimental and testing equipments, such as: NMR (Bruker 400M)、HPLC、chiral-HPLC、LC-MS、LC-MS/MS (API 4000)、IR、UV、GC、GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope...

R&D Team

Jindun Medical has a group of professional R&D personnel, and employs many domestic and foreign drug synthesis experts to guide R&D, making our synthesis more accurate and efficient.

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Case-Sharing

We have helped several top domestic pharmaceutical companies, such as Hansoh, Hengrui and HEC Pharm. Here we will show part of them.

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Customzation Case One:

Cas No.: 110351-94-5

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Customzation Case Two:

Cas No.: 144848-24-8

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Customzation Case Three:

Cas No.: 200636-54-0

Cooperation Mode

1.Customize New Intermediates or APIs. Same as above case sharing, customers have the demands for specific Intermediates or APIs, and they can not find the needed products in the market,  then we can help to Customize.

2.Process Optimization for Old Products. Our team will help to Optimize and improve such production whose reaction route is old, production cost is high, and the efficiency is low. We can provide full documentation for technology transfer and process improvement, help customer for a more efficient production.

From drug targets to INDs, JIN DUN Medical provides you with one-stop personalized R&D solutions.

JIN DUN Medical insists on creating a team with dreams, making dignified products, meticulous, rigorous, and going all out to be a trusted partner and friend of customers!


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