100% Original Factory Dosing In Water Treatment - 3-Amino-4-pyrazole carbosamide hemisulfate – JIN DUN

Short Description:

Product Detail

Product Tags

Feedback (2)

We can normally fulfill our respected consumers with our great excellent, great value and good provider due to we're much more specialist and extra hard-working and do it in cost-effective way for Polyvinylpyrrolidone K30, Demineralization Process Of Water Softening, Reverse Osmosis Water Treatment, We promise to try our best to provide you with high quality and efficient services.

100% Original Factory Dosing In Water Treatment - 3-Amino-4-pyrazole carbosamide hemisulfate – JIN DUN Detail:

Intermediate for the synthesis of allopurinol.

It is one of the 3-amino-4-substituted pyrazole series. It can be used as an intermediate to synthesize many pharmacologically effective organic compounds, such as allopurinol, one of the pyrazolopyrimidine derivatives series, the latter since 1963 Since its clinical use, it has been the main drug for the treatment of gout. At present, there are few known methods for synthesizing

3-aminopyrazole-4-carboxamide hemisulfate in China, mainly by reacting malononitrile and triethyl orthoformate to prepare ethoxymethylene malononitrile, and then with The reaction of hydrazine hydrate yields 3-amino-4-cyanopyrazole, which is finally reacted with concentrated sulfuric acid to produce

3-aminopyrazole-4-carboxamide hemisulfate (Chen Huiru, Xiao Guomin et al. 3-aminopyrazole- Synthesis of 4-formamide hemisulfate [J]. Chemical Industry Times, 2008, 6 (22): 39 40), the total yield of synthesis by this method is about 60% (calculated as malononitrile), this method It involves a three-step reaction, the steps are longer, and the reagents used, such as malononitrile and ethoxymethylene malononitrile, are more toxic and expensive. In addition, the 3-aminopyrazole-4 prepared by this method -Formamide hemisulfate has a color that is difficult to remove and requires additional processing, which is more complicated.

There are reports in foreign literature using pyridylamide hydrazone and ethoxymethylene malononitrile as raw materials to obtain 3-amino-4-cyanopyrazole by addition and cyclization, and then react with concentrated sulfuric acid to obtain the target compound (Reuken G Jones. Reactions of orthoesters with activemethylene compounds[J]. J Am Chem Soc. 1952,74(5) :4889 4891). The main raw materials used in this method are expensive, the reaction yield is not high, and the profit of industrial production is low. It must be difficult.

Executive standard: Enterprise Standard
Exterior: Off-white or yellow powder

Package: 25kg/drum
assay（HPLC）content Greater than or equal to 98.0%
purity（HPLC）content Greater than or equal to 99.5%

Product detail pictures:

Related Product Guide:

We are also specializing in improving the things management and QC method in order that we could retain terrific edge inside the fiercely-competitive small business for 100% Original Factory Dosing In Water Treatment - 3-Amino-4-pyrazole carbosamide hemisulfate – JIN DUN , The product will supply to all over the world, such as: Rwanda, New Zealand, Grenada, They are sturdy modeling and promoting effectively all over the world. Never ever disappearing major functions within a quick time, it's a have to in your case of fantastic good quality. Guided by the principle of "Prudence, Efficiency, Union and Innovation. the corporation. ake an excellent efforts to expand its international trade, raise its organization. rofit and raise its export scale. We have been confident that we've been going to have a bright prospect and to be distributed all over the world in the years to come.

Aqueous Processing